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Substance P (NK1) receptor expression by human colonic epithelial cell line Caco-2

✍ Scribed by S Böckmann

Book ID
117408390
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
484 KB
Volume
23
Category
Article
ISSN
0196-9781

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Neurokinin-1 receptor (NK-1R) expression
Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P
✍ Triona Goode; Terry O'Connor; Ann Hopkins; Derek Moriarty; Gearld C. O'Sullivan; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 628 KB

## Abstract We have previously shown that the receptor for substance P (SP), neurokinin‐1 receptor (NK‐1R), is a marker of human mucosal but not peripheral mononuclear cells. In the present study, we investigate NK‐1R expression in the human colonic mucosa in vivo, particularly in the epithelial ce