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196 Identification of a Novel Substance P (SP)-Neurokinin-1 Receptor (NK-1R) MicroRNA-221 Inflammatory Network in Human Colonic Epithelial Cells

✍ Scribed by Fang, Kai; Sideri, Aristea; Law, Ivy Ka Man; Bakirtzi, Kyriaki; Koon, Hon Wai; Oikonomopoulos, Angelos; Hommes, Daniel W.; Iliopoulos, Dimitrios; Pothoulakis, Charalabos

Book ID: 122214311
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 50 KB
Volume: 146
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(14)60179-7

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Neurokinin-1 receptor (NK-1R) expression

Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P

✍ Triona Goode; Terry O'Connor; Ann Hopkins; Derek Moriarty; Gearld C. O'Sullivan; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 628 KB

## Abstract We have previously shown that the receptor for substance P (SP), neurokinin‐1 receptor (NK‐1R), is a marker of human mucosal but not peripheral mononuclear cells. In the present study, we investigate NK‐1R expression in the human colonic mucosa in vivo, particularly in the epithelial ce