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DNA breaks and cell cycle arrest induced by okadaic acid in Caco-2 cells, a human colonic epithelial cell line

✍ Scribed by A. Traoré; I. Baudrimont; S. Ambaliou; S.D. Dano; E.E. Creppy

Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
317 KB
Volume
75
Category
Article
ISSN
0340-5761

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## Abstract Cyclooxygenase 2 (COX‐2) has been suggested to be associated with liver carcinogenesis. Several reports have shown that NSAIDs inhibit the growth of hepatocellular carcinoma cell lines. There is little evidence of how COX‐2 inhibitors regulate the proliferation of hepatocellular carcino