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Cytokine induced expression of substance P (NK-1) receptors in human colonic epithelial cells

✍ Scribed by Goode, T.; O'Connell, J.; O'Sullivan, G.C.; Collins, J.K.; Shanahan, F.

Book ID
122720678
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
180 KB
Volume
114
Category
Article
ISSN
0016-5085

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Neurokinin-1 receptor (NK-1R) expression
Neurokinin-1 receptor (NK-1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P
✍ Triona Goode; Terry O'Connor; Ann Hopkins; Derek Moriarty; Gearld C. O'Sullivan; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 628 KB

## Abstract We have previously shown that the receptor for substance P (SP), neurokinin‐1 receptor (NK‐1R), is a marker of human mucosal but not peripheral mononuclear cells. In the present study, we investigate NK‐1R expression in the human colonic mucosa in vivo, particularly in the epithelial ce