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Study of hepatitis C virus entry in genetically humanized mice

โœ Scribed by Dorner, Marcus; Rice, Charles M.; Ploss, Alexander

Book ID
121718571
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
770 KB
Volume
59
Category
Article
ISSN
1046-2023

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Hepatitis C virus (HCV) remains a major medical problem. Antiviral treatment is only partially effective and a vaccine does not exist. Development of more effective therapies has been hampered by the lack of a suitable small animal model. Although xenotransplantation of immunodeficient mice with hum