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Development of Humanized Mice for the Study of Hepatitis C Virus Infection

✍ Scribed by P. Turrini; R. Sasso; S. Germoni; I. Marcucci; A. Celluci; A. Di Marco; E. Marra; G. Paonessa; A. Eutropi; R. Laufer; G. Migliaccio; J. Padron


Book ID
116932307
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
209 KB
Volume
38
Category
Article
ISSN
0041-1345

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Hepatitis C virus (HCV) remains a major medical problem. Antiviral treatment is only partially effective and a vaccine does not exist. Development of more effective therapies has been hampered by the lack of a suitable small animal model. Although xenotransplantation of immunodeficient mice with hum