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Studies on the Role of the Ah Receptor in Hexachlorobenzene-Induced Porphyria

โœ Scribed by MARK E. HAHN; THOMAS A. GASIEWICZ; PATRICIA LINKO; JOYCE A. GOLDSTEIN

Book ID
119860587
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
122 KB
Volume
514
Category
Article
ISSN
0890-6564

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Male C57Bl/10 mice were chronically fed hexachlorobenzene (HCB) (0.02% of the diet) alone or in combination with a single subcutaneous dose of iron (12.5 mg iron per mouse). After eight weeks the group of mice pretreated with the iron overload was highly sensitized to the porphyrogenic effect of HCB