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The iron effect on the mitochondrial porphyrin in the hexachlorobenzene induced experimental porphyria

โœ Scribed by Morimoto, Akio; Imai-Matsumura, Kyoko; Murakami, Naotoshi

Book ID
122353156
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
60 KB
Volume
1
Category
Article
ISSN
0168-8278

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Hepatic mitochondrial oxidative metaboli
Hepatic mitochondrial oxidative metabolism and lipid peroxidation in experimental hexachlorobenzene-induced porphyria with dietary carbonyl iron overload
โœ Edward S. Feldman; Bruce R. Bacon ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 713 KB

Both human porphyria cutanea tarda and experimental hexachlorobenzene-induced porphyria are associated with hepatic injury and are potentiated by excess hepatic iron. The mechanisms whereby cellular injury occurs and the synergistic role of iron overload are unknown. In the present experiments, we s