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Studies on the Regioselectivity of the Cyclization of Tryptophanol-Derived Oxazolopiperidone Lactams

✍ Scribed by Amat, Mercedes; Llor, Núria; Subrizi, Fabiana; Pérez, Maria; Molins, Elies; Bosch, Joan


Book ID
119958049
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
550 KB
Volume
2013
Category
Article
ISSN
1434-193X

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The synthesis of tricyclic lactam building blocks by the radical addition-cyclization-elimination (RACE) reaction is presented. A range of oxime ethers carrying unsaturated ester part have been tested for the radical reaction. A variety of substituents were incorporated around the aromatic backbones