The structure and dynamics of the ionophoric antibiotic monensin in the presence of micelles have been determined. The conformation of monensin was derived from 50 nuclear Overhauser enhancement (NOE) derived distance restraints and metric-matrix based distance geometry calculations. The conformatio
Studies on the ionophorous antibiotics. Part III. The structure of lonomycin, a polyether antibiotic
✍ Scribed by Noboru Ōtake; Mitsuo Koenuma; Hiroshi Miyamae; Shoichi Sato; Yoshihiko Saito
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 178 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Lonomycin') is an antibiotic elaborated by Streptomyces ribosidificus and shows an antimicrobial activity against gram-positive bacteria including mycobacteria as well as some kind of filsmentous fungi. Lonomycin is also effective in the treatment of coccidial infections
📜 SIMILAR VOLUMES
## Salinomycin' is a new antibiotic elaborated by the strain of Streptomyces aZbus and has an antimicrobial activity against Gram-positive bacteria, mycobacteria and fungi. Furthermore, salinomycin is effective in the treatment of coccidial infections in poultry. In light of its biological activi
The carboxylic acid antibiotic A-23187 (A) is a divalent cation ionophore which has been isolated from cultures of Streptomyces chartreusensis.' The structure and proposed absolute configuration2 have shown it to be one of a limited group of natural products, including oligomycin B3 and aplysiatoxin
We recently reported the first total synthesis of lasalocid A (11.' One of the key intermediates in this synthesis is the isolasalocid ketone 11, which was synthesized by a 19-step procedure in about 3.5% overall yield from a readily