✦ LIBER ✦
Synthetic studies on polyether antibiotics. III. A stereocontrolled synthesis of isolasalocid ketone from acyclic precursors.
✍ Scribed by T. Nakata; Y. Kishi
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 216 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
We recently reported the first total synthesis of lasalocid A (11.' One of the key intermediates in this synthesis is the isolasalocid ketone 11, which was synthesized by a 19-step procedure in about 3.5% overall yield from a readily