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Studies on serum-mediated inhibition of cellular immunity to spontaneous mouse mammary tumors

✍ Scribed by G. H. Heppner

Publisher
John Wiley and Sons
Year
1969
Tongue
French
Weight
554 KB
Volume
4
Category
Article
ISSN
0020-7136

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✦ Synopsis

Sera from mice which have either spontaneously developed a mamniury tumor, or which have been immunized against such a tumor, have been shown capable of abrogating the ability of lymph-node cells from these mice to specifically inhibit colony formation by mammary tumor cells in vitro. Sera jrom mice sensitized to another, independently arising, syngeneic mammary tumor or to a syngeneic Moloney sarcoma virus-induced tumor are less active in this respect, indicating that this reaction is specific. I t is suggested that these observations are related to the in vivo phenomenon called imniunological enhancement .

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