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Studies on Pyrrolidinones. An Improved Synthesis of Pyroglutamoyl Chloride

✍ Scribed by Rigo, Benoit; El Ghammarti, Samira; Gautret, Philippe; Couturier, Daniel

Book ID
111890155
Publisher
Taylor and Francis Group
Year
1994
Tongue
English
Weight
326 KB
Volume
24
Category
Article
ISSN
0039-7911

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Studies on pyrrolidinones. Synthesis of
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✍ Natacha Malecki; Raymond Houssin; Jean-Pierre Héanichart; Daniel Couturier; Ferd 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 75 KB

## Abstract Dimethyl 7‐methoxycarbonylmethyl‐5‐oxo‐1,2,3,5‐tetrahydro‐indolizine‐3,8‐dicarboxylate was synthesized starting from methyl pyroglutamate. A study was made of the reactions of this highly functionalized pyridone with ethyl iodide, selenium oxide, isoamyl nitrite and formaldehyde. Litera