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Studies on pyrrolidinones. Synthesis of some N-fatty acylpyroglutamic acids

✍ Scribed by BenoÎT Rigo; Antonios Kolokouris; Nicolas Kolokouris

Book ID
112131356
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
281 KB
Volume
32
Category
Article
ISSN
0022-152X

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Studies on pyrrolidinones. Synthesis of
Studies on pyrrolidinones. Synthesis of N-benzhydrylpyroglutamic acids and esters
✍ Benoît Rigo; Philippe Gautret; Anne Legrand; Jean Pierre Hénichart; Daniel Coutu 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 331 KB

## Abstract Catalyzed __N__‐alkylation of __N,O__‐bistrimethylsilyl pyroglutamic acid with trimethylsilyl benzhydryl ethers yields trimethylsilyl __N__‐benzhydrylpyroglutamates. Hydrolysis of these compounds or saponification of the methyl esters gives the corresponding acids.