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Studies on pyrrolidinones. Synthesis of N-benzhydrylpyroglutamic acids and esters

✍ Scribed by Benoît Rigo; Philippe Gautret; Anne Legrand; Jean Pierre Hénichart; Daniel Couturier

Publisher
Journal of Heterocyclic Chemistry
Year
1998
Tongue
English
Weight
331 KB
Volume
35
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Catalyzed N‐alkylation of N,O‐bistrimethylsilyl pyroglutamic acid with trimethylsilyl benzhydryl ethers yields trimethylsilyl N‐benzhydrylpyroglutamates. Hydrolysis of these compounds or saponification of the methyl esters gives the corresponding acids.

📜 SIMILAR VOLUMES

ChemInform Abstract: Studies on Pyrrolid
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