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Studies on pyrrolidinone. Synthesis of aza analogs of podophyllotoxin and related compounds

✍ Scribed by Anne Legrand; Benoît Rigo; Philippe Gautret; Jean-Pierre Henichart; Daniel Couturier

Publisher
Journal of Heterocyclic Chemistry
Year
1999
Tongue
English
Weight
443 KB
Volume
36
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

The Friedel‐Crafts cyclisation of N‐benzhydrylpyroglutamic acids whose aromatic rings are substituted by methoxy or methylenedioxy groups gives podophyllotoxin analogs whose lactone ring was changed to a lactam.

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