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Studies on pyrrolidinones. synthesis of N-(2-nitrobenzyl)pyroglutamic acid

✍ Scribed by BenoǏT Rigo; RÉGis Dolaine; Samira El Ghammarti; Daniel Couturier


Book ID
118284444
Publisher
Journal of Heterocyclic Chemistry
Year
1996
Tongue
English
Weight
210 KB
Volume
33
Category
Article
ISSN
0022-152X

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✍ Anne Legrand; Benoît Rigo; Jean-Pierre Hénichart; Bernadette Norberg; Fabrice Ca 📂 Article 📅 2000 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 871 KB

## Abstract Condensation of trimethoxyphenyl naphthylcarbinol trimethylsilyl ether with methyl __N__‐trimethylsilyl‐pyroglutamate yields two separable esters. The Friedel‐Crafts cyclization of the acids obtained after saponification gives analogs of azapodophylloxin. Reduction and treatment of the