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Studies on pyrrolidinones. A convenient synthesis of 5-cyano-2-pyrrolidinone derivatives

✍ Scribed by Benoǐt Rigo; Charles Lespagnol; Marc Pauly


Book ID
112128120
Publisher
Journal of Heterocyclic Chemistry
Year
1986
Tongue
English
Weight
143 KB
Volume
23
Category
Article
ISSN
0022-152X

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Studies on pyrrolidinones. Synthesis of
✍ Natacha Malecki; Raymond Houssin; Jean-Pierre Héanichart; Daniel Couturier; Ferd 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 75 KB

## Abstract Dimethyl 7‐methoxycarbonylmethyl‐5‐oxo‐1,2,3,5‐tetrahydro‐indolizine‐3,8‐dicarboxylate was synthesized starting from methyl pyroglutamate. A study was made of the reactions of this highly functionalized pyridone with ethyl iodide, selenium oxide, isoamyl nitrite and formaldehyde. Litera