Studies of the HER-2/neu Proto-Oncogene in Human Breast Cancer
β Scribed by Dennis J. Slamon; William Godolphin; Axel Ullrich; Michael F. Press
- Book ID
- 119104263
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 73 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0165-4608
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Background. It is unclear whether HER-O/neu proto-oncogene expression in ovarian epithelial neoplasms is related to prognosis. Methods. The authors performed immunohistochemical stains on 20 serous tumors of low malignant potential (STLMP) in Stages I and I1 and 19 serious carcinomas in the same st
## Abstract Assessment of __HER2/neu__ oncogene has been used as both a prognostic and predictive marker for breast cancer. However, the choice of the best method to assess the status of __HER2/neu__ oncogene in breast cancer tissue remains controversial. A variety of techniques are available to de
## Abstract The cβ__erb__ Bβ2/__neu__ gene encodes a cellβsurface glycoprotein with extensive homology to, but distinct from, the epidermal growthβfactor receptor. In this study, we compared the cβ__erb__ Bβ2/__neu__ gene amplification and expression of tissue specimens obtained from the bladders o