FISH detection of HER-2/neu oncogene amplification in early onset breast cancer
β Scribed by Wei-Rong Xing; Kennedy W. Gilchrist; Charles P. Harris; Wilner Samson; Lorraine F. Meisner
- Book ID
- 105315225
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 799 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0167-6806
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## Abstract Assessment of __HER2/neu__ oncogene has been used as both a prognostic and predictive marker for breast cancer. However, the choice of the best method to assess the status of __HER2/neu__ oncogene in breast cancer tissue remains controversial. A variety of techniques are available to de
Total tumor cathepsin D (TCD) levels were determined prospectively by a radioimmunometric assay in tumor c y t o d of 858 primary breast cancer patients diagnosed between 1989-1991. In 581 of these patients, tumor HER-l/neu oncogene amplification was simultaneously determined. In a "traininset" of 3