Total tumor cathepsin D (TCD) levels were determined prospectively by a radioimmunometric assay in tumor c y t o d of 858 primary breast cancer patients diagnosed between 1989-1991. In 581 of these patients, tumor HER-l/neu oncogene amplification was simultaneously determined. In a "traininset" of 3
Amplification of the HER-2/neu oncogene is uncommon in pediatric osteosarcomas
β Scribed by Anirban Maitra; Dana Wanzer; Arthur G. Weinberg; Raheela Ashfaq
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 504 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0008-543X
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## Abstract The cβ__erb__ Bβ2/__neu__ gene encodes a cellβsurface glycoprotein with extensive homology to, but distinct from, the epidermal growthβfactor receptor. In this study, we compared the cβ__erb__ Bβ2/__neu__ gene amplification and expression of tissue specimens obtained from the bladders o