Mechanisms of escape from CD8+ T-cell cl
โ
Koji Kono; Eva Halapi; Christina Hising; Max Petersson; Eva Gerdin; Farkas Vanky
๐
Article
๐
1997
๐
John Wiley and Sons
๐
French
โ 208 KB
๐ 3 views
We have developed an in vitro model to study mechanisms by which ovarian tumor cells that over-express the HER-2/ neu proto-oncogene escape recognition by T CD8 1 . Nine tumorspecific, HLA A2-restricted T CD8 1 clones were isolated from 2 ovarian tumor-specific T CD8 1 lines derived from tumorinfilt