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Pre-existent immunity to the HER-2/neu oncogenic protein in patients with HER-2/neu overexpressing breast and ovarian cancer

✍ Scribed by Mary L. Disis; Keith L. Knutson; Kathy Schiffman; Kristine Rinn; Douglas G. McNeel

Book ID
110235438
Publisher
Springer US
Year
2000
Tongue
English
Weight
77 KB
Volume
62
Category
Article
ISSN
0167-6806

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## Abstract Strong expression of human epidermal growth factor receptor 2 (HER‐2)/neu in breast cancer has been associated with poor prognosis. Reduced expression of p27^Kip1^, a cyclin‐dependent kinase inhibitor, correlates with poor clinical outcome in breast cancer. In this study, we provide a c