✦ LIBER ✦

Studies of immune complexes

✍ Scribed by Paul H. Plotz

Publisher: John Wiley and Sons
Year: 1982
Tongue: English
Weight: 479 KB
Volume: 25
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780251002

No coin nor oath required. For personal study only.

✦ Synopsis

As for incurable diseases there are countless cures and for curable ones but a few, so for elusive diseases there are countless diagnostic maneuvers and for those we comprehend but a few, and for entities we cannot clearly define, there are countless laboratory tests, and for those we can, but a few.

We appear to be at flood tide for the development of assays for those elusive entities, immune complexes, and for the application of those assays to elusive diseases-not just to rheumatologic diseases, but diseases in every category. If we have indeed come to the time where more restraint of both research energies and editorial liberality lies before us, there are good reasons. There is, I think, a sense of disappointment about what has been learned. Assays for immune complexes are diagnostic of no disease, they correlate with no particular clinical manifestations, and they probably do not even accurately point to a particular pathogenetic mechanism.

If these assays are not living up to their expec-From the

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