The structure of capuramycin has been determined to be an uracll nucleoside with a caprolactam substltuent as shown in Fig. 5 by NMR spectral analysis, chemical degradation and X-ray analysis. During the course of our screening program for new antibiotics, it was found that Streptomyces nrlseus 446
Structure of a new class of C-nucleoside antibiotic, showdomycin
✍ Scribed by Yuzo Nakagawa; Hideo Kan̄o; Yoshiko Tsukuda; Hirozo Koyama
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- French
- Weight
- 236 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Some attempts to obtain a more simple crystalline derivative containing o heavy atom and suitable for the analysis were unsuccessful. Reduction with lithium aluminum deuteride afforded bisdeoxo N-methylcycloshowdomycin acetonide-d4. The details was read by one of us, Tsukudo at the 20th Annual Meeting of the Chemical Society of Japan, March 1967, and will be published in the Chemical Communication.
📜 SIMILAR VOLUMES
The structure of a new antibiotic, roseophilin, was elucidated to be as shown iu Fig. 1 by NMR spectral analysis including a variety of two-dimensional techniques. Roseophilin was found to possess a novel skeleton containing pyrrole and furan moieties.