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Structure-Based Predictors of Resistance to the HIV-1 Integrase Inhibitor Elvitegravir

✍ Scribed by Masso, Majid; Chuang, Grace; Jain, Shinar; Hao, Kate; Vaisman, Iosif I.

Book ID
122319100
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
34 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Abstract We used genotypic and phylogenetic analysis to determine integrase diversity among subtypes, and studied natural polymorphisms and mutations implicated in resistance to integrase inhibitors (INI) in treatment‐naΓ―ve persons (n = 220) and ‐experienced individuals (n = 24). Phylogenetics r