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Genetic Barrier to the Development of Resistance to Integrase Inhibitors in HIV-1 Subtypes CRF01_AE and B

✍ Scribed by Nguyen, Hai Le; Ruxrungtham, Kiat; Delaugerre, Constance


Book ID
121184896
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
264 KB
Volume
55
Category
Article
ISSN
0300-5526

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## Abstract We used genotypic and phylogenetic analysis to determine integrase diversity among subtypes, and studied natural polymorphisms and mutations implicated in resistance to integrase inhibitors (INI) in treatment‐naΓ―ve persons (n = 220) and ‐experienced individuals (n = 24). Phylogenetics r