𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of HIV-1 integrase by modified oligonucleotides: Optimization of the inhibitor structure

✍ Scribed by T. A. Prikazchikova; E. M. Volkov; E. M. Zubin; E. A. Romanova; M. B. Gottikh


Book ID
110174424
Publisher
SP MAIK Nauka/Interperiodica
Year
2007
Tongue
English
Weight
178 KB
Volume
41
Category
Article
ISSN
0026-8933

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Development of the next generation of HI
✍ Victor Hadi; Yung-Hyo Koh; Tino Wilson Sanchez; Danielle Barrios; Nouri Neamati; πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 522 KB

HIV-1 integrase (IN), one of the essential enzymes in HIV infection, has been validated as a target for HIV treatment. While more than 20 drugs have been approved by the FDA to treat HIV/AIDS, only one drug, Raltegravir (1), was approved as an IN inhibitor. The rapid mutation of the virus, which lea