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Discovery and Structure–Activity Relationship Studies of a Unique Class of HIV-1 Integrase Inhibitors

✍ Scribed by Raveendra Dayam; Tino Sanchez; Nouri Neamati


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
337 KB
Volume
1
Category
Article
ISSN
1860-7179

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## Abstract Structure‐based quantitative structure‐activity relationship (QSAR) studies on a series of checkpoint kinase 1 (Chk1) inhibitors were performed to find the key structural features responsible for their inhibitory activity. Molecular docking was employed to explore the binding mode of al