✦ LIBER ✦

Structure-Activity Relationships among Inhibitors of Peptidylglycine Amidating Monooxygenase

✍ Scribed by C. HARKER RHODES; CHARLES HONSINGER

Book ID: 119869697
Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 200 KB
Volume: 689
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.1993.tb55622.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Potent and selective inhibitors of human

Potent and selective inhibitors of human peptidylglycine α-amidating monooxygenase

✍ Cao, Feihua; Gamble, Allan B.; Kim, Hye-Kyung; Onagi, Hideki; Gresser, Mary J.; 📂 Article 📅 2011 🏛 The Royal Society of Chemistry 🌐 English ⚖ 97 KB

Synthesis of tripeptide inhibitors of pe

Synthesis of tripeptide inhibitors of peptidylglycine α-amidating monooxygenase (PAM) containing D- and L-styrylglycine

✍ Mark D. Andrews; Kelly A. O'Callaghan; John C. Vederas 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 745 KB

Both enantiomers of (E)-and (Z)-2-amino-4-phenyl-3-butenoic acids (styrylglycines) 1 la,b and 12a,b, were synthesised in non-racemic form, in 7 steps starting from either D-or L-aspartic acid. (E)-Styrylglycine l la was converted to the tripeptide D-Phe-L-Phe-D-styrylglycine 15, and also to three di

Amidation of Bioactive Peptides: The Str

Amidation of Bioactive Peptides: The Structure of Peptidylglycine -Hydroxylating Monooxygenase

✍ Prigge, S. T. 📂 Article 📅 1997 🏛 American Association for the Advancement of Scienc 🌐 English ⚖ 987 KB

Thiorphan, tiopronin, and related analog

Thiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine α-amidating monooxygenase (PAM)

✍ Neil R. McIntyre; Edward W. Lowe Jr.; Geoffrey H. Chew; Terrence C. Owen; David 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 874 KB

Determination of peptidylglycine α-amida

Determination of peptidylglycine α-amidating monooxygenase activity in human serum by thin-layer chromatography

✍ Noriyuki Miyazaki; Tomihiko Uemura 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 539 KB

We developed a simple assay system for the quantitative evaluation of peptidylglycine alpha-amidating monooxygenase activity using as substrate a 125I-labeled synthetic tripeptide, 125I-D-Tyr-Val-Gly, thin-layer chromatography, and a radiochromatoscanner. The basic principle of this method is that t

ChemInform Abstract: Synthesis of Tripep

ChemInform Abstract: Synthesis of Tripeptide Inhibitors of Peptidylglycine α- Amidating Monooxygenase (PAM) Containing D- and L-Styrylglycine.

✍ M. D. ANDREWS; K. A. O'CALLAGHAN; J. C. VEDERAS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB

Synthesis of Tripeptide Inhibitors of Peptidylglycine α-Amidating Monooxygenase (PAM) Containing D-and L-Styrylglycine. -The tripeptides (XI)-(XIV) do not show potent inhibition of peptidylglycine α-amidating monooxygenase. -(ANDREWS, M. D.; O'CALLAGHAN, K.