Stereoselective total synthesis of (−)-cleistenolide
✍ Scribed by Dokuburra Chanti Babu; Jondoss Jon Paul Selavam; Dorigondla Kumar Reddy; Vanam Shekhar; Yenamandra Venkateswarlu
- Book ID
- 108283564
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 347 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
The total synthesis of (À)-cleistenolide, a novel natural product recently isolated from the annonaceae species cleistochlamys kirkii oliver, is described. The synthesis proceeds starting from easily accessible D-manitol using a selective benzoylation, a selective acetonide deprotection, silylprotec
## Abstract An efficient and short total synthesis of (−)‐cleistenolide (**1**) from D‐mannitol with an overall yield of 23.6% is described. The chiron approach for the synthesis of (−)‐cleistenolide involves a one‐C‐atom __Wittig__ olefination, a selective allylic triethylsilyl protection, and a _