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Stereoselective Synthesis of the C3−C17 Bis-Oxane Domain of Phorboxazole A

✍ Scribed by Cink, Russell D.; Forsyth, Craig J.


Book ID
126417062
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
158 KB
Volume
62
Category
Article
ISSN
0022-3263

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The macrocyclic domain of phorboxazole A
✍ David R Williams; Michael P Clark 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 192 KB

A stereoselective synthesis of the C1~232 macrocyclic domain of phorboxazole A is described. Key steps have examined the convergent linkage of two major components for the formation of the CI9--C20 (E)-alkene, and the subsequent intramolecular (Z)olefination at C2-C 3 for ring closure of the macrocy