Synthesis of tritium labelled 7-dehydroc
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Dennis P. Michaud; Nashaat T. Nashed; Donald M. Jerina
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Article
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1986
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John Wiley and Sons
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French
β 235 KB
We report the synthesis of tritiated 7-dehydrocholesterol 5@,6B-oxide in high specific activity. Oxidation of 7a-bromocholesterol 5B16B-oxide to the 3-keto epoxide followed by borotritide reduction, in a special buffer-organic solvent system to minimize undesired rearrangement, regenerated the 3B-hy