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Stereoselective radical addition of tertiary amines to (5R)-5-menthyloxy-2[5H]-furanone: Application to the enantioselective synthesis of (−)-isoretronecanol and (+)-laburnine

✍ Scribed by Samuel Bertrand; Norbert Hoffmann; Jean-Pierre Pete

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
138 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

The adducts of a stereoselective radical addition of tertiary amines with (5R)-5-menthyloxy-2[5H]-furanone were transformed very efficiently into enantiomerically pure pyrrolizidine and indolizidine alkaloids, through a three steps sequence.

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