ChemInform Abstract: Highly Efficient and Stereoselective Radical Addition of Tertiary Amines to Electron-Deficient Alkenes — Application to the Enantioselective Synthesis of Necine Bases.
✍ Scribed by Samuel Bertrand; Norbert Hoffmann; Jean-Pierre Pete
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 42 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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📜 SIMILAR VOLUMES
Application to the Enantioselective Synthesis of (-)-Isoretronecanol and (+)-Laburnine. -Compound (I) is an adduct of a stereoselective radical addition of a tertiary amine with (5R)-5-menthyloxy-2[5H]-furanone. It is readily transformed to (+)-laburnine (IV) in a three-step sequence. Similarly, (-