Stereocontrolled Syntheses of 24(S),25-Epoxycholesterol and Related Oxysterols for Studies on the Activation of LXR Receptors. -The title epoxide (IV) and derivatives thereof such as (V) and (VII) are prepared as interesting ligands and functional activators of LXR receptors. It is noteworthy that (
โฆ LIBER โฆ
Stereocontrolled syntheses of 24(S),25-epoxycholesterol and related oxysterols for studies on the activation of LXR receptors
โ Scribed by E.J. Corey; Michael J. Grogan
- Book ID
- 104260314
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 193 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Efficient syntheses are described of desmosterol ( 4), the corresponding 24(S),25 epoxide ( 6) and various analogs of 6 for evaluation as ligands and functional activators of LXR receptors.
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