ChemInform Abstract: Simple, Stereocontrolled Syntheses of 24(S),25-Epoxy-22(R)-hydroxycholesterol, 22(R),24(S)-Dihydroxycholesterol and Diastereomers, New Ligands for Binding and Activation of LXRs.

ChemInform Abstract: Stereocontrolled Sy

ChemInform Abstract: Stereocontrolled Syntheses of 24(S),25-Epoxycholesterol and Related Oxysterols for Studies on the Activation of LXR Receptors.

✍ E. J. Corey; Michael J. Grogan 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB

Stereocontrolled Syntheses of 24(S),25-Epoxycholesterol and Related Oxysterols for Studies on the Activation of LXR Receptors. -The title epoxide (IV) and derivatives thereof such as (V) and (VII) are prepared as interesting ligands and functional activators of LXR receptors. It is noteworthy that (