Stereochemistry of the proposed intermediates in the biosynthesis of mycinamicins
β Scribed by Seiichi Takano; Yoshinori Sekiguchi; Youichi Shimazaki; Kunio Ogasawara
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 128 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Recently a new intermediate in the biosynthesis of squalene has been obtained from farnesyl pyrophosphate as substrate in a yeast homogenate containing minimal amounts of reduced nicotinamide adenine di-'nucleotide (NADP-H) (1). On the basis of a number of experimental results, structure I was sugge
## Abstract **Mg motors**: We characterized the in vitro function of MycE and MycF, two __O__βmethyltransferases involved in the biosynthesis of mycinamicin antibiotics. Each enzyme was confirmed to be an __S__βadenosylβLβmethionine (SAM)βdependent deoxysugar methyltransferase. Their optimal activi