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Stem Cell Transplantation

✍ Scribed by Rafael Matesanz (auth.), Carlos López-Larrea PhD, Antonio López-Vázquez MD, Beatriz Suárez-Álvarez PhD (eds.)

Publisher
Springer-Verlag New York
Year
2012
Tongue
English
Leaves
364
Series
Advances in Experimental Medicine and Biology 741
Edition
1
Category
Library
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✦ Synopsis

Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields—areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.

✦ Table of Contents

Front Matter....Pages i-xxv
The Frontiers of Organ Transplantation and Cell Therapy....Pages 1-12
Organ Transplantation in the 21th Century....Pages 13-26
Imunology and the Challenge of Transplantation....Pages 27-43
Cellular Immunotolerance in the Transplant....Pages 44-59
Immunosuppression in the ERA of Biological Agents....Pages 60-72
Transgenic Organs and Xenotransplants....Pages 73-88
Cell and Tissue Therapy in Regenerative Medicine....Pages 89-102
Characteristics of Adult Stem Cells....Pages 103-120
Bone Marrow Transplantation Extends Its Scope....Pages 121-134
Biology of Stem Cells: The Role of Microenvironments....Pages 135-151
Mobilization and Homing of Hematopoietic Stem Cells....Pages 152-170
Great Promise of Tissue-Resident Adult Stem/Progenitor Cells in Transplantation and Cancer Therapies....Pages 171-186
Multipotent Mesenchymal Stromal Cells: Clinical Applications and Cancer Modeling....Pages 187-205
Neural Stem Cells and Transplantation Studies in Parkinson’s Disease....Pages 206-216
Biological Impact of Human Embryonic Stem Cells....Pages 217-230
Epigenetics of Embryonic Stem Cells....Pages 231-253
New Tools in Regenerative Medicine: Gene Therapy....Pages 254-275
Therapeutic Cloning and Cellular Reprogramming....Pages 276-289
Advances in Stem Cell Therapy....Pages 290-313
Tissue Bioengineering and Artificial Organs....Pages 314-336
Back Matter....Pages 337-342

✦ Subjects

Stem Cells; Cancer Research

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