Hematopoietic Stem Cell Transplantation

✍ Scribed by Elizabeth O. Hexner, Stephen G. Emerson (auth.), Robert J. Soiffer MD (eds.)

• Publisher: Humana Press
• Year: 2008
• Tongue: English
• Leaves: 726
• Series: Contemporary hematology
• Edition: 2
• Category: Library

✦ Synopsis

Remarkable developments in the field of transplantation have created opportunities to address the formidable challenges of transplantation across histocompatibility barriers, stem cell expansion, and prevention of complications and generation of graft-vs-tumor activity to eradicate residual disease. Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair. The updated chapters introduce the biologic underpinnings of hematopoietic cell transplantation, basic stem cell biology, immunobiology, and histocompatibility, with emphasis on indications and results of transplantation for specific diseases. Written by experts in the field, Stem Cell Transplantation for Hematologic Disorders, Second Edition provides seasoned professionals with a complete understanding of the current state of transplantation biology as well as a clear vision into the future.

✦ Table of Contents

Front Matter....Pages i-xvi
Stem Cell Biology....Pages 3-18
Stem Cell Transplantation for Hematologic Malignancies....Pages 19-38
Immunobiology of Transplantation....Pages 39-54
Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia in the Adult....Pages 57-82
Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia....Pages 83-104
Stem Cell Transplantation for Hodgkin's and Non-Hodgkin's Lymphomas....Pages 105-136
Transplantation in Chronic Lymphocytic Leukemia....Pages 137-147
Stem Cell Transplantation in Multiple....Pages 149-166
Allogeneic Hematopoietic Cell Transplantation for Patients with Myelodysplastic Syndrome and Myeloproliferative Disorders....Pages 167-182
Stem Cell Transplantation for Marrow Failure....Pages 183-200
Stem Cell Transplantation for Hemoglobinopathies....Pages 201-221
Stem Cell Sources for Allogeneic Transplantation....Pages 225-244
Allogeneic Unrelated Donor Blood and Marrow Transplantation....Pages 245-265
Umbilical Cord Hematopoietic Stem Cell Transplantation....Pages 267-288
Haploidentical Stem Cell Transplantation....Pages 289-317
Ablative Preparative Regimens for Hematopoietic Stem Cell Transplantation....Pages 321-347
Nonmyeloablative Transplantation....Pages 349-374
Immune Reconstitution after Allogeneic Transplantation....Pages 377-420
Infection in the Hematopoietic Stem Cell Transplant Recipient....Pages 421-448
EBV Lymphoproliferative Disease after Transplantation....Pages 449-465
Hepatic Veno-Occlusive Disease....Pages 467-493
Lung Injury after Hematopoietic Stem Cell Transplantation....Pages 495-536
Quality of Life Issues Post-Transplantation....Pages 537-559
Pathophysiology of Acute Graft-versus-Host Disease....Pages 563-588
Acute Graft-versus-Host Disease....Pages 589-620
Chronic Graft-versus-Host Disease....Pages 621-649
Graft Manipulation: T Cell Depletion and Tumor Cell Purging....Pages 653-686
Donor Lymphocyte Infusions Clinical Applications and the Graft‐versus‐Leukemia Effect....Pages 687-710
Regenerative Medicine: Application in Cardiovascular Diseases....Pages 713-724
Back Matter....Pages 725-736

✦ Subjects

Hematology; Oncology; Blood Transfusion Medicine; Internal Medicine