Hematopoietic Stem Cell Transplantation

✍ Scribed by Sergio Giralt, Michael R. Bishop (auth.), Michael R. Bishop (eds.)

• Publisher: Springer US
• Year: 2009
• Tongue: English
• Leaves: 592
• Series: Cancer Treatment and Research 144
• Edition: 1
• Category: Library

✦ Synopsis

Hematopoietic Stem Cell Transplantation reviews pertinent aspects of both autologous and allogeneic stem cell transplantation and our current understanding of transplantation biology including T cell and natural killer cell biology, HLA expression, and post-transplant immune reconstitution. The unique aspect to this volume is that each chapter is co-authored by experts in their respective fields from different institutions to provide potentially different perspectives on each topic. This book provides a very current and succinct overview of hematopoietic stem cell transplantation that is complimentary to the larger texts on the field.

"There have beendramatic advancesin the application of hematopoietic stem cell transplantation for the treatment of malignant disease. This text provides a comprehensive update of the progress in the field. Technical and therapeutic innovations are reviewed by a distinguished assemblage of talented investigators." Steven T. Rosen, M.D., Series Editor

✦ Table of Contents

Front Matter....Pages i-xv
Principles and Overview of Allogeneic Hematopoietic Stem Cell Transplantation....Pages 1-21
The Principles and Overview of Autologous Hematopoietic Stem Cell Transplantation....Pages 23-45
Natural Killer Cell Activity and Killer Immunoglobulin-Like Receptors in Hematopoietic Stem Cell Transplantation....Pages 47-69
Advancement and Clinical Implications of HLA Typing in Allogeneic Hematopoietic Stem Cell Transplantation....Pages 71-94
Immunogenomics and Proteomics in Hematopoietic Stem Cell Transplantation: Predicting Post-Hematopoietic Stem Cell Transplant Complications....Pages 95-129
Clinical Implications of Immune Reconstitution Following Hematopoietic Stem Cell Transplantation....Pages 131-154
Functionally Defined T Cell Subsets in Transplantation Biology and Therapy: Regulatory T Cells and Th2 Cells....Pages 155-186
Understanding and Enhancing the Graft-Versus-Leukemia Effect After Hematopoietic Stem Cell Transplantation....Pages 187-208
Reduced-Intensity and Nonmyeloablative Conditioning Regimens....Pages 209-232
Umbilical Cord Blood Transplantation....Pages 233-255
Biology and Management of Acute Graft-Versus-Host Disease....Pages 257-275
Biology and Management of Chronic Graft-Versus-Host Disease....Pages 277-298
Radioimmunoconjugates in Hematopoietic Stem Cell Transplantation....Pages 299-315
Evolving Indications for Hematopoietic Stem Cell Transplantation in Multiple Myeloma and Other Plasma Cell Disorders....Pages 317-355
Role of Hematopoietic Stem Cell Transplantation in the Treatment of Non-Hodgkin’s Lymphoma....Pages 357-397
The Role of Hematopoietic Stem Cell Transplantation in Hodgkin Lymphoma....Pages 399-414
Role of Hematopoietic Stem Cell Transplantation in Acute Myelogenous Leukemia and Myelodysplastic Syndrome....Pages 415-439
Allogeneic Hematopoietic Stem Cell Transplantation for Adult Acute Lymphoblastic Leukemia....Pages 441-454
Hematopoietic Stem Cell Transplantation in Children and Adolescents with Malignant Disease....Pages 455-496
Cellular Adoptive Immunotherapy After Autologous and Allogeneic Hematopoietic Stem Cell Transplantation....Pages 497-537
Improvements in the Prevention and Management of Infectious Complications After Hematopoietic Stem Cell Transplantation....Pages 539-573
Back Matter....Pages 575-589

✦ Subjects

Oncology; Hematology