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Statistical tests of genetic association for case-control study designs

✍ Scribed by Wang, K.

Book ID
124154896
Publisher
Oxford University Press
Year
2012
Tongue
English
Weight
150 KB
Volume
13
Category
Article
ISSN
1465-4644

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What's the best statistic for a simple test of genetic association in a case-control study?
✍ Chia-Ling Kuo; Eleanor Feingold πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 132 KB πŸ‘ 2 views

## Abstract Genome‐wide genetic association studies typically start with univariate statistical tests of each marker. In principle, this single‐SNP scanning is statistically straightforwardβ€”the testing is done with standard methods (e.g. Ο‡^2^ tests, regression) that have been well studied for decad