𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Genetic case-control association studies – correcting for multiple testing

✍ Scribed by Dale R. Nyholt

Book ID
106133573
Publisher
Springer
Year
2001
Tongue
English
Weight
20 KB
Volume
109
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Resampling-based multiple hypothesis tes
Resampling-based multiple hypothesis testing procedures for genetic case-control association studies
✍ Bingshu E. Chen; Lori C. Sakoda; Ann W. Hsing; Philip S. Rosenberg 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 265 KB 👁 1 views

## Abstract In case‐control studies of unrelated subjects, gene‐based hypothesis tests consider whether any tested feature in a candidate gene—single nucleotide polymorphisms (SNPs), haplotypes, or both—are associated with disease. Standard statistical tests are available that control the false‐pos

A joint association test for multiple SN
A joint association test for multiple SNPs in genetic case-control studies
✍ Tao Wang; Howard Jacob; Soumitra Ghosh; Xujing Wang; Zhao-Bang Zeng 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 222 KB 👁 1 views

## Abstract For a dense set of genetic markers such as single nucleotide polymorphisms (SNPs) on high linkage disequilibrium within a small candidate region, a haplotype‐based approach for testing association between a disease phenotype and the set of markers is attractive in reducing the data comp

Direct assessment of multiple testing co
Direct assessment of multiple testing correction in case-control association studies with related individuals
✍ Zuoheng Wang 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 1 views

Genome-wide association studies typically test large numbers of genetic variants in association with trait values. It is well known that linkage disequilibrium (LD) between nearby markers tends to introduce correlation among association tests. Failure to properly adjust for multiple comparisons can