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Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

✍ Scribed by Mark H Kaplan; Ulrike Schindler; Stephen T Smiley; Michael J Grusby

Book ID
117722804
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
156 KB
Volume
4
Category
Article
ISSN
1074-7613

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## Abstract Many genes implicated in Th1 and Th2 differentiation have been identified in both human and mouse. However, the functional roles and hierarchy of these factors in the signaling pathways leading to either Th1 or Th2 responses are less clear. To explore at which stage of polarization the