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IgM-mediated signaling is required for the development of a normal B cell memory response

✍ Scribed by Linjie Guo; Xuejun Zhang; Biao Zheng; Shuhua Han

Book ID
116756687
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
982 KB
Volume
45
Category
Article
ISSN
0161-5890

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## Abstract In this study it has been investigated whether the interaction of antigen and B cell surface immunoglobulin (sIg) is required for full clonal expansion of memory B cells specific for the hapten, p‐azophenyl‐lactoside (lac). Cultures of lac‐primed B cells and keyhole limpet hemocyanin (K