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IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

✍ Scribed by Sergei Grivennikov; Eliad Karin; Janos Terzic; Daniel Mucida; Guann-Yi Yu; Sivakumar Vallabhapurapu; Jürgen Scheller; Stefan Rose-John; Hilde Cheroutre; Lars Eckmann; Michael Karin


Book ID
113523864
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
38 KB
Volume
15
Category
Article
ISSN
1535-6108

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✍ John J. Grzesiak; Kathy C. Smith; Douglas W. Burton; Leonard J. Deftos; Michael 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 620 KB

## Abstract We have demonstrated recently that PTHrP is upregulated in pancreatic adenocarcinoma and that the ECM exerts regulatory control, at least in part, over PTHrP expression. In our present study, we examined the potential signaling interactions between these 2 pathways. Our results demonstr