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Stacking interaction of guanine with netropsin in the minor groove of d(CGTATATACG)2

โœ Scribed by Nicola G.A Abrescia; Lucy Malinina; Juan A Subirana


Book ID
115629797
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
379 KB
Volume
294
Category
Article
ISSN
0022-2836

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Accessibility of the minor groove of DNA
โœ A. F. Melnikova; A. S. Zasedatelev; A. M. Kolchinsky; G. V. Gursky; A. L. Zhuze; ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› Springer ๐ŸŒ English โš– 380 KB

The interaction of the antibiotics distamycin A, distamycin analogue and netropsin with chromatin of calf thymus has been studied by circular dichroism measurements and by gel filtration. The minor groove of DNA in chromatin is accessible by 83-89% to the binding of these antibiotics as compared wit