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Spectrum of MTHFR gene SNPs C677T and A1298C: a study among 23 population groups of India

โœ Scribed by Kallur Nava Saraswathy; Mohammad Asghar; Ratika Samtani; Benrithung Murry; Prakash Ranjan Mondal; Pradeep Kumar Ghosh; Mohinder Pal Sachdeva

Book ID
106471575
Publisher
Springer
Year
2011
Tongue
English
Weight
212 KB
Volume
39
Category
Article
ISSN
0301-4851

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Methylenetetrahydrofolate reductase (MTHFR): The incidence of mutations C677T and A1298C in the Ashkenazi Jewish population
โœ Rady, Peter L.; Tyring, Stephen K.; Hudnall, S. David; Vargas, Trini; Kellner, L ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 36 KB ๐Ÿ‘ 2 views

The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy