𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metabolic effects of C677T and A1298C mutations at the MTHFR gene in Brazilian children with neural tube defects

✍ Scribed by Andrea L.A Cunha; Mario H Hirata; Chong A Kim; Elvira M Guerra-Shinohara; Kymio Nonoyama; Rosario D.C Hirata

Book ID
117074534
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
128 KB
Volume
318
Category
Article
ISSN
0009-8981

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Linkage disequilibrium of MTHFR genotype
Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects(NTD)
✍ Stegmann, Karolin; Ziegler, Andreas; Ngo, Ernestine T. K. M.; Kohlschmidt, Nicol πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 32 KB πŸ‘ 1 views

A number of studies have demonstrated that the common polymorphism 677C→T in the gene encoding 5, 10-methylenetetrahydrofolate reductase (MTHFR) leads to a thermolabile variant with decreased enzyme activity and to mildly elevated plasma homocysteine. 677TT homozygosity was shown to be more frequent

A1298C polymorphism of the MTHFR gene an
A1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico
✍ Lizbeth Gonzalez-Herrera; Ileana Castillo-Zapata; Guadalupe Garcia-Escalante; Do πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 85 KB πŸ‘ 2 views

## Abstract ## BACKGROUND: Methylenetetrahydrofolate reductase (__MTHFR__) of the folate metabolism pathway is a candidate gene for neural tube defects (NTDs). Frequency of the second common polymorphism, A1298C, in the __MTHFR__ gene is not well known in Mexico. Conflicting results exist regardin