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MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients

✍ Scribed by Fakhraddin Naghibalhossaini; Pooneh Mokarram; Islam Khalili; Mohammad Vasei; Seyed Vahid Hosseini; Hassan Ashktorab; Mozhgan Rasti; Kourosh Abdollahi

Book ID: 113513682
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 551 KB
Volume: 197
Category: Article
ISSN: 0165-4608
DOI: 10.1016/j.cancergencyto.2009.11.014

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## Abstract The common functional methylenetetrahydrofolate reductase (__MTHFR__) C677T polymorphism may influence the risk of colorectal cancer (CRC), but data from published studies with individually low statistical power are conflicting. To clarify the role of __MTHFR__ C677T genotype in CRC, we